About Excel run slowly and often crash issue. first please reference Microsoft’s solution.
and the also do the same
1.First please make sure that all the OS and Office update patch installed successfully. You can check on "software center" and "control pan". Then restart computer.
2.Make sure Antivirus software is already up to date.
3.Open Excel—File—Advanced—Uncheck the "Disable hardware graphics acceleration"
4.Set the default printer to “CutePDF”, do not allow excel auto connect to office printer.
5.Use Office Configuration Analyzer Tool (OffCAT) check the issue.